USB2250/50i/51/51i Data Sheet

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 2009 - 2015 Microchip Technology Inc.

DS00002005A-page 1

General Description

The Microchip USB2250/50i/51/51i is a USB 2.0 com-
pliant, Hi-Speed mass storage class peripheral control-
ler intended for reading and writing to more than 24
popular flash media formats from the CompactFlash

®

(CF), SmartMedia

TM

 (SM), xD-Picture Card

TM

 (xD)

1

,

Memory Stick

®

 (MS), Secure Digital (SD), and MultiMe-

diaCard

TM

 (MMC) families. 

The USB2250/50i/51/51i is a fully integrated, single
chip solution capable of ultra high performance opera-
tion. Average sustained transfer rates exceeding 35
MB/s are possible if the media and host can support
those rates. 

Highlights

• 128-pin VTQFP (14x14 mm) RoHS compliant 

package

• Targeted for applications in which single or 

"combo" media sockets are used

• Supports multiple simultaneous card insertions
• Flexible assignment of number of LUNs and how 

card types are associated with the LUNs

• Hardware-controlled data flow architecture for all 

self-mapped media

• Pipelined hardware support for access to non-

self-mapped media

• Order number with “i” denotes the version that 

supports the industrial temperature range of -40ºC 
to 85ºC

Hardware Features

• Single chip flash media controller with non-multi-

plexed interface for independent card sockets

• Flash Media Specification Revision Compliance

- CompactFlash 4.1
- Secure Digital 2.0
- MultiMediaCard 4.2

• MMC Streaming Mode support

- Memory Stick 1.43
- Memory Stick Pro Format 1.02
- Memory Stick Duo Format 1.10
- Memory Stick Pro-HG Duo Format 1.01
- xD-Picture Card 1.2
- SmartMedia 1.3

• Extended configuration options

- xD player mode operation 
- Socket switch polarities, etc.

• Media Activity LED
• On board 24 MHz crystal driver circuit
• Optional external 24 MHz clock input

- 4 Independent internal card power FETs
- 200 mA each 
- "Fold-back" short circuit protection

• 8051 8-bit microprocessor

- 60 MHz - single cycle execution
- 64 KB ROM | 14 KB RAM

• Internal regulator for 1.8 V core operation
• Optimized pinout improves signal routing which 

eases implementation for improved signal integ-
rity

OEM Selectable

• Vendor, product, and language IDs
• Manufacturer ID and product strings (28 charac-

ter)

• Serial number string (12h digit max)
• Customizable vendor specific data by optional 

use of external serial EEPROM

• Bus- or self-powered selection
• LED blink interval or duration
• Internal power FET configuration

Software Features

• Optimized for low latency interrupt handling
• Reduced memory footprint
• Device Firmware Upgrade (DFU) support of exter-

nal EEPROM or External Flash
- Assembly line support
- End user field upgrade support
- DFU Package consists of driver, firmware, 

sample DFU application and source code, 
DFU driver API

• Optional custom firmware with up to 128 KB 

external ROM 

Applications

• Flash Media Card Reader/Writer
• Printers
• Desktop and Mobile PCs
• Consumer A/V
• Media Players/Viewers
• Vista ReadyBoost

TM

1.) xD-Picture Card not applicable to USB2251.

USB2250/50i/51/51i

Ultra Fast USB 2.0 Multi-Slot Flash Media Controller

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USB2250/50i/51/51i

DS00002005A-page 2

 2009 - 2015 Microchip Technology Inc.

TO OUR VALUED CUSTOMERS

It is our intention to provide our valued customers with the best documentation possible to ensure successful use of your Microchip
products. To this end, we will continue to improve our publications to better suit your needs. Our publications will be refined and
enhanced as new volumes and updates are introduced. 

If you have any questions or comments regarding this publication, please contact the Marketing Communications Department via
E-mail at 

docerrors@microchip.com

. We welcome your feedback.

Most Current Data Sheet

To obtain the most up-to-date version of this data sheet, please register at our Worldwide Web site at:

http://www.microchip.com

You can determine the version of a data sheet by examining its literature number found on the bottom outside corner of any page. 
The last character of the literature number is the version number, (e.g., DS30000000A is version A of document DS30000000).

Errata

An errata sheet, describing minor operational differences from the data sheet and recommended workarounds, may exist for cur-
rent devices. As device/documentation issues become known to us, we will publish an errata sheet. The errata will specify the
revision of silicon and revision of document to which it applies.

To determine if an errata sheet exists for a particular device, please check with one of the following:
• Microchip’s Worldwide Web site; 

http://www.microchip.com

• Your local Microchip sales office (see last page)

When contacting a sales office, please specify which device, revision of silicon and data sheet (include -literature number) you are
using.

Customer Notification System

Register on our web site at 

www.microchip.com

 to receive the most current information on all of our products.

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 2009 - 2015 Microchip Technology Inc.

DS00002005A-page 3

USB2250/50i/51/51i

Table of Contents

1.0 Introduction  ..................................................................................................................................................................................... 4
2.0 Pin Configuration  ............................................................................................................................................................................ 6
3.0 Block Diagram ................................................................................................................................................................................. 7
4.0 Pin Table  ......................................................................................................................................................................................... 8
5.0 Pin Descriptions  ............................................................................................................................................................................ 10
6.0 Pin Reset State Table  ................................................................................................................................................................... 17
7.0 Configuration Options  ................................................................................................................................................................... 21
8.0 AC Specifications  .......................................................................................................................................................................... 32
9.0 DC Parameters  ............................................................................................................................................................................. 34
10.0 Package Outline .......................................................................................................................................................................... 38
Appendix A: Data Sheet Revision History ........................................................................................................................................... 39
Product Identification System  ............................................................................................................................................................. 40
The Microchip Web Site  ...................................................................................................................................................................... 41
Customer Change Notification Service  ............................................................................................................................................... 41
Customer Support  ............................................................................................................................................................................... 41

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 2009 - 2015 Microchip Technology Inc.

DS00002005A-page 4

USB2250/50i/51/51i

1.0

INTRODUCTION

The Microchip USB2250/50i/51/51i is a flash media card reader solution fully compliant with the USB 2.0 specification.
All required resistors on the USB ports are integrated into the device. This includes all series termination resistors on
D+ and D– pins and all required pull-down and pull-up resistors. The over-current sense inputs for the downstream fac-
ing ports have internal pull-up resistors.

Hardware Features

• Single chip flash media controller

• USB2250/USB2251 supports the commercial temperature range of 0°C to +70°C

• USB2250i/USB2251i supports the industrial temperature range of -40°C to +85°C

• 8051 8-bit microprocessor

- 60 MHz - single cycle execution

- 64 KB ROM |14 KB RAM

• Integrated regulator for 1.8 V core operation

• Flash Media Card Specification Revision Compliance

• Compact Flash 4.1

- CF UDMA Modes 0-4

- CF PIO Modes 0-6

• Secure Digital 2.0 

- HS-SD and HC-SD

- TransFlash™ and reduced form factor media 

• MultiMediaCard 4.2

- 1/4/8 bit MMC

• Memory Stick 1.43 

• Memory Stick Pro Format 1.02

• Memory Stick Pro-HG Duo Format 1.01 

- Memory Stick, MS Duo, HS-MS, MS Pro-HG, MS Pro

• Memory Stick Duo 1.10

• Smart Media 1.3

• xD-Picture Card 1.2

Software Features

• If the OEM is using an external EEPROM, the following features are available:

- Customizable vendor, product, and device ID’s

- 12-hex digits maximum for the serial number string

- 28-character manufacturer ID and product strings for the flash media reader/writer

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USB2250/50i/51/51i

DS00002005A-page 5

 2009 - 2015 Microchip Technology Inc.

1.1

Acronyms

ATA:

 Advanced Technology Attachment

CFC: 

Compact Flash Controller

FET: 

Field Effect Transistor

LUN: 

Logical Unit Number

MMC: MultiMediaCard

MSC: 

Memory Stick Controller

PLL: Phase-Locked 

Loop

RoHS: 

Restriction of Hazardous Substances Directive

RXD: 

Received eXchange Data

SDC: Secure 

Digital 

Controller

SIE: 

Serial Interface Engine

SMC: 

SmartMedia Controller

True IDE Mode:  True Integrated Drive Electronics Mode

TXD: 

Transmit eXchange Data

UART: Universal 

Asynchronous 

Receiver-Transmitter

UCHAR: Unsigned 

Character

UINT: 

Unsigned Integer

VTQFP: 

Very Thin Quad Flat Package

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 2009 - 2015 Microchip Technology Inc.

DS00002005A-page 6

USB2250/50i/51/51i

2.0

PIN CONFIGURATION

FIGURE 2-1:

128-PIN VTQFP DIAGRAM

97

MS_D6

99

MS_D3

100

MS_D7

101

MS_SCLK

102

VSS

103

TEST

104

VDD33

106

MA7

107

MA13

108

MA6

109

MA8

110

MA5

111

MA9

112

MA4

113

MA11

114

MA3

115

nMRD

116

MA2

117

CF_DMARQ / RXD

SCL / xD_ID

CF_DMACK

120

LED  

121

VBUS_DET

122

VSS

123

XTAL2

124

XTAL1 (CLKIN)

125

VDD18PLL

126

VSS

127

RBIAS

128

VDD33

64

nRESET

63

CF_D5

62

CF_D12

61

CF_D4

60

CF_D11

59

CF_D3

58

CF_nCD

57

SM_nCD

56

SM_nB/R

55

SM_nRE

54

SM_nCE

53

SM_CLE

52

SM_ALE

51

VSS

50

VDD33

49

VDD18

48

SM_nWE

47

SM_nWP

46

SM_D0

45

SM_D1

44

SM_D2

43

SM_D3

42

SM_D4

41

SM_D5

40

SM_D6

39

SM_D7

38

SM_nWPS

37

MD0

36

MD1

35

MD2

34

MD3

33

MD7

96

MS

_

D

2

95

MS

_

D

4

94

M

S

_D0 /

 MS

_

S

DIO

93

MS

_

D

5

92

MS

_

D

1

91

MS

_

B

S

90

CF

_D10

89

CF

_D9

88

CF

_D2

87

CF

_D8

86

CF

_D1

85

CF

_D0

84

CF

_SA0

83

CF

_SA1

82

CF

_SA2

81

VS

S

80

CF

_IORDY

79

CF

_nRESET

78

CR

D_PW

R1

77

V

DD33

76

CR

D_PW

R2

75

VS

S

74

CF

_IRQ

73

CF

_nIOW

72

CF

_nIOR

71

CF

_nCS0

70

CF

_D15

69

CF

_D7

68

CF

_D14

67

CF

_D6

66

CF

_D13

65

V

DD33

USB225X

128 VTQFP 

(Top View)

1

MA12

2

MA15

3

nM

WR

4

MA14

5

SD

A

6

REG_EN

7

USB+

8

US

B-

9

VSS

10

SD_

D

1

11

SD_

D

6

12

SD_

D

0

13

SD_

D

7

15

VDD33

16

17

VSS

18

SD_CLK

19

SD_

D

5

20

SD_

C

MD

21

SD_

D

4

22

SD_

D

3

23

SD_

D

2

24

MA10

25

MA1 /

 CL

K_S

E

L1

26

nMCE

27

MA0 /

 CL

K_S

E

L0

28

MA16

29

MD

6

30

MD

5

31

MD

4

SD

_n

CD

14

CRD

_PWR

0

118

CRD

_PWR

3

119

32

98

MS_INS

105

SD_WP

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 2009 - 2015 Microchip Technology Inc.

DS00002005A-page 7

USB2250/50i/51/51i

3.0

BLOCK DIAGRAM

FIGURE 3-1:

USB2250/50I/51/51I BLOCK DIAGRAM

FMDU

CTL

8051

PROCESSOR

SFR 

RAM

CF/

GPIO (16)

MS

SM

RAM

USB 

Host

AUTO_CBW 

PROC

PHY

FMI

XDATA  BRIDGE

+ BUS ARBITER

BUS 

INTFC

BUS 

INTFC

BUS 

INTFC

    

EP0 TX

EP0 RX

EP2 TX

EP2 RX

EP1 RX
EP1 TX

ROM

64 KB

RAM

10 KB

ADDR

MAP

PWR_FET1

PWR_FET3

CRD_PWR0

CRD_PWR1

CRD_PWR3

Clock 

Generation and 

Control

CRD_PWR2

SD/

MMC

4K

total

PWR_FET0

PWR_FET2

GPIOs

Program Memory I/O Bus

3.3 V

1.8 V Reg

VDD18

3.3 V

VDD18PLL

PLL

24 MHz 

Crystal

SIE

CTL

1.8 V Reg

USB2250 / USB2251

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DS00002005A-page 8

USB2250/50i/51/51i

4.0

PIN TABLE

4.1

128-Pin Package

TABLE 4-1:

128-PIN VTQFP PACKAGE

COMPACT FLASH INTERFACE (28 PINS)

CF_D0

CF_D1

CF_D2

CF_D3

CF_D4

CF_D5

CF_D6

CF_D7

CF_D8

CF_D9

CF_D10

CF_D11

CF_D12

CF_D13

CF_D14

CF_D15

CF_nIOR

CF_nIOW

CF_IRQ

CF_nRESET

CF_IORDY

CF_nCS0

CF_DMACK

CF_SA0

CF_SA1

CF_SA2

CF_nCD

CF_DMARQ

SMARTMEDIA INTERFACE (17 PINS)

SM_D0

SM_D1

SM_D2

SM_D3

SM_D4

SM_D5

SM_D6

SM_D7

SM_ALE

SM_CLE

SM_nRE

SM_nWE

SM_nWP

SM_nB/R

SM_nCE

SM_nCD

SM_nWPS

MEMORY STICK INTERFACE (11 PINS)

MS_BS

MS_D0 / MS_SDIO

MS_SCLK

MS_INS

MS_D1

MS_D2

MS_D3

MS_D4

MS_D5

MS_D6

MS_D7

SECURE DIGITAL / MULTIMEDIACARD INTERFACE (12 PINS)

SD_CMD

SD_CLK

SD_D0

SD_D1

SD_D2

SD_D3

SD_WP

SD_nCD

SD_D4

SD_D5

SD_D6

SD_D7

USB INTERFACE (6 PINS)

USB+

USB-

RBIAS

XTAL2

XTAL1 (CLKIN)

REG_EN

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USB2250/50i/51/51i

DS00002005A-page 9

 2009 - 2015 Microchip Technology Inc.

MEMORY/IO INTERFACE (28 PINS)

MA0 / CLK_SEL0

MA1 / CLK_SEL1

MA2

MA3

MA4

MA5

MA6

MA7

MA8

MA9

MA10

MA11

MA12

MA13

MA14

MA15

MA16

MD0

MD1

MD2

MD3

MD4

MD5

MD6

MD7

nMRD

nMWR

nMCE

MISC (10 PINS)

nRESET

VBUS_DET

SCL / xD_ID

SDA

 LED

CRD_PWR0

CRD_PWR1

CRD_PWR2

CRD_PWR3

TEST

DIGITAL, POWER (16 PINS)

(6) VDD33

(8) VSS

VDD18

VDD18PLL

TOTAL 128

TABLE 4-1:

128-PIN VTQFP PACKAGE (CONTINUED) 

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DS00002005A-page 10

USB2250/50i/51/51i

5.0

PIN DESCRIPTIONS

This section provides a detailed description of each signal. The signals are arranged in functional groups according to
their associated interface. The pin descriptions are applied when using the internal default firmware and can be refer-
enced in 

Section 7.0, "Configuration Options," on page 21

. Please reference 

Section 1.1, "Acronyms," on page 5

 for a

list of the acronyms used.

The “n” symbol in the signal name indicates that the active, or asserted, state occurs when the signal is at a low voltage
level. When “n” is not present in the signal name, the signal is asserted at the high voltage level.

The terms assertion and negation are used exclusively. This is done to avoid confusion when working with a mixture of
“active low” and “active high” signals. The term assert, or assertion, indicates that a signal is active, independent of
whether that level is represented by a high or low voltage. The term negate, or negation, indicates that a signal is inac-
tive.

5.1

128-Pin VTQFP Pin Descriptions

TABLE 5-1:

USB2250/50I/51/51I 128-PIN VTQFP PIN DESCRIPTIONS

Name

Symbol

128-Pin 

VTQFP

Buffer 

Type

Description

COMPACT FLASH (CF) INTERFACE

CF Chip Select 0

CF_nCS0

71

O12PU

This pin is the active low chip select 0 signal for 
the task file registers of the CF ATA device in 
True IDE mode. This pin has a weak internal 
pull-up resistor.

CF Register 
Address

CF_SA[2:0]

82
83
84

I/O12

These pins are the register select address bits 
for the CF ATA device.

CF Interrupt

CF_IRQ

74

IPD

This is the active high interrupt request signal 
from the CF device. This pin has a weak internal 
pull-down resistor.

CF Data 15-8

CF_D[15:8] /

70
68
66
62
60
90
89
87

I/O12PD

CF_D[15:8]: These pins are the bi-directional 
data signals CF_D15 - CF_D8 in True IDE mode 
data transfer.

In True IDE mode, all task file register 
operations occur on CF_D[7:0], while data 
transfer occurs on CF_D[15:0].

These bi-directional data signals have weak 
internal pull-down resistors.

CF Data 7-0

CF_D[7:0]

69
67
63
61
59
88
86
85

I/O12PD

CF_D[7:0]: These pins are the bi-directional 
data signals CF_D7 - CF_D0 in True IDE mode 
data transfer. In True IDE mode, all of the task 
file register operations occur on CF_D[7:0], 
while data transfer occurs on CF_D[15:0].

These bi-directional data signals have weak 
internal pull-down resistors.

IO Ready

CF_IORDY

80

IPU

This pin is the active high input signal for 
IORDY. This pin has a weak internal pull-up 
resistor.

CF Card 
Detection1

CF_nCD

58

I/O12

Designates as the Compact Flash card 
detection pin.

CF Hardware 
Reset

CF_RESET_N

79

O12

This pin is an active low hardware reset signal 
to the CF device.

CF IO Read

CF_nIOR

72

O12

This pin is an active low read strobe signal for 
the CF device.

CF IO Write 
Strobe

CF_nIOW

73

O12

This pin is an active low write strobe signal for 
the CF device.

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 2009 - 2015 Microchip Technology Inc.

DS00002005A-page 1

General Description

The Microchip USB2250/50i/51/51i is a USB 2.0 com-
pliant, Hi-Speed mass storage class peripheral control-
ler intended for reading and writing to more than 24
popular flash media formats from the CompactFlash

®

(CF), SmartMedia

TM

 (SM), xD-Picture Card

TM

 (xD)

1

,

Memory Stick

®

 (MS), Secure Digital (SD), and MultiMe-

diaCard

TM

 (MMC) families. 

The USB2250/50i/51/51i is a fully integrated, single
chip solution capable of ultra high performance opera-
tion. Average sustained transfer rates exceeding 35
MB/s are possible if the media and host can support
those rates. 

Highlights

• 128-pin VTQFP (14x14 mm) RoHS compliant 

package

• Targeted for applications in which single or 

"combo" media sockets are used

• Supports multiple simultaneous card insertions
• Flexible assignment of number of LUNs and how 

card types are associated with the LUNs

• Hardware-controlled data flow architecture for all 

self-mapped media

• Pipelined hardware support for access to non-

self-mapped media

• Order number with “i” denotes the version that 

supports the industrial temperature range of -40ºC 
to 85ºC

Hardware Features

• Single chip flash media controller with non-multi-

plexed interface for independent card sockets

• Flash Media Specification Revision Compliance

- CompactFlash 4.1
- Secure Digital 2.0
- MultiMediaCard 4.2

• MMC Streaming Mode support

- Memory Stick 1.43
- Memory Stick Pro Format 1.02
- Memory Stick Duo Format 1.10
- Memory Stick Pro-HG Duo Format 1.01
- xD-Picture Card 1.2
- SmartMedia 1.3

• Extended configuration options

- xD player mode operation 
- Socket switch polarities, etc.

• Media Activity LED
• On board 24 MHz crystal driver circuit
• Optional external 24 MHz clock input

- 4 Independent internal card power FETs
- 200 mA each 
- "Fold-back" short circuit protection

• 8051 8-bit microprocessor

- 60 MHz - single cycle execution
- 64 KB ROM | 14 KB RAM

• Internal regulator for 1.8 V core operation
• Optimized pinout improves signal routing which 

eases implementation for improved signal integ-
rity

OEM Selectable

• Vendor, product, and language IDs
• Manufacturer ID and product strings (28 charac-

ter)

• Serial number string (12h digit max)
• Customizable vendor specific data by optional 

use of external serial EEPROM

• Bus- or self-powered selection
• LED blink interval or duration
• Internal power FET configuration

Software Features

• Optimized for low latency interrupt handling
• Reduced memory footprint
• Device Firmware Upgrade (DFU) support of exter-

nal EEPROM or External Flash
- Assembly line support
- End user field upgrade support
- DFU Package consists of driver, firmware, 

sample DFU application and source code, 
DFU driver API

• Optional custom firmware with up to 128 KB 

external ROM 

Applications

• Flash Media Card Reader/Writer
• Printers
• Desktop and Mobile PCs
• Consumer A/V
• Media Players/Viewers
• Vista ReadyBoost

TM

1.) xD-Picture Card not applicable to USB2251.

USB2250/50i/51/51i

Ultra Fast USB 2.0 Multi-Slot Flash Media Controller

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USB2250/50i/51/51i

DS00002005A-page 2

 2009 - 2015 Microchip Technology Inc.

TO OUR VALUED CUSTOMERS

It is our intention to provide our valued customers with the best documentation possible to ensure successful use of your Microchip
products. To this end, we will continue to improve our publications to better suit your needs. Our publications will be refined and
enhanced as new volumes and updates are introduced. 

If you have any questions or comments regarding this publication, please contact the Marketing Communications Department via
E-mail at 

docerrors@microchip.com

. We welcome your feedback.

Most Current Data Sheet

To obtain the most up-to-date version of this data sheet, please register at our Worldwide Web site at:

http://www.microchip.com

You can determine the version of a data sheet by examining its literature number found on the bottom outside corner of any page. 
The last character of the literature number is the version number, (e.g., DS30000000A is version A of document DS30000000).

Errata

An errata sheet, describing minor operational differences from the data sheet and recommended workarounds, may exist for cur-
rent devices. As device/documentation issues become known to us, we will publish an errata sheet. The errata will specify the
revision of silicon and revision of document to which it applies.

To determine if an errata sheet exists for a particular device, please check with one of the following:
• Microchip’s Worldwide Web site; 

http://www.microchip.com

• Your local Microchip sales office (see last page)

When contacting a sales office, please specify which device, revision of silicon and data sheet (include -literature number) you are
using.

Customer Notification System

Register on our web site at 

www.microchip.com

 to receive the most current information on all of our products.

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 2009 - 2015 Microchip Technology Inc.

DS00002005A-page 3

USB2250/50i/51/51i

Table of Contents

1.0 Introduction  ..................................................................................................................................................................................... 4
2.0 Pin Configuration  ............................................................................................................................................................................ 6
3.0 Block Diagram ................................................................................................................................................................................. 7
4.0 Pin Table  ......................................................................................................................................................................................... 8
5.0 Pin Descriptions  ............................................................................................................................................................................ 10
6.0 Pin Reset State Table  ................................................................................................................................................................... 17
7.0 Configuration Options  ................................................................................................................................................................... 21
8.0 AC Specifications  .......................................................................................................................................................................... 32
9.0 DC Parameters  ............................................................................................................................................................................. 34
10.0 Package Outline .......................................................................................................................................................................... 38
Appendix A: Data Sheet Revision History ........................................................................................................................................... 39
Product Identification System  ............................................................................................................................................................. 40
The Microchip Web Site  ...................................................................................................................................................................... 41
Customer Change Notification Service  ............................................................................................................................................... 41
Customer Support  ............................................................................................................................................................................... 41

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 2009 - 2015 Microchip Technology Inc.

DS00002005A-page 4

USB2250/50i/51/51i

1.0

INTRODUCTION

The Microchip USB2250/50i/51/51i is a flash media card reader solution fully compliant with the USB 2.0 specification.
All required resistors on the USB ports are integrated into the device. This includes all series termination resistors on
D+ and D– pins and all required pull-down and pull-up resistors. The over-current sense inputs for the downstream fac-
ing ports have internal pull-up resistors.

Hardware Features

• Single chip flash media controller

• USB2250/USB2251 supports the commercial temperature range of 0°C to +70°C

• USB2250i/USB2251i supports the industrial temperature range of -40°C to +85°C

• 8051 8-bit microprocessor

- 60 MHz - single cycle execution

- 64 KB ROM |14 KB RAM

• Integrated regulator for 1.8 V core operation

• Flash Media Card Specification Revision Compliance

• Compact Flash 4.1

- CF UDMA Modes 0-4

- CF PIO Modes 0-6

• Secure Digital 2.0 

- HS-SD and HC-SD

- TransFlash™ and reduced form factor media 

• MultiMediaCard 4.2

- 1/4/8 bit MMC

• Memory Stick 1.43 

• Memory Stick Pro Format 1.02

• Memory Stick Pro-HG Duo Format 1.01 

- Memory Stick, MS Duo, HS-MS, MS Pro-HG, MS Pro

• Memory Stick Duo 1.10

• Smart Media 1.3

• xD-Picture Card 1.2

Software Features

• If the OEM is using an external EEPROM, the following features are available:

- Customizable vendor, product, and device ID’s

- 12-hex digits maximum for the serial number string

- 28-character manufacturer ID and product strings for the flash media reader/writer

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USB2250/50i/51/51i

DS00002005A-page 5

 2009 - 2015 Microchip Technology Inc.

1.1

Acronyms

ATA:

 Advanced Technology Attachment

CFC: 

Compact Flash Controller

FET: 

Field Effect Transistor

LUN: 

Logical Unit Number

MMC: MultiMediaCard

MSC: 

Memory Stick Controller

PLL: Phase-Locked 

Loop

RoHS: 

Restriction of Hazardous Substances Directive

RXD: 

Received eXchange Data

SDC: Secure 

Digital 

Controller

SIE: 

Serial Interface Engine

SMC: 

SmartMedia Controller

True IDE Mode:  True Integrated Drive Electronics Mode

TXD: 

Transmit eXchange Data

UART: Universal 

Asynchronous 

Receiver-Transmitter

UCHAR: Unsigned 

Character

UINT: 

Unsigned Integer

VTQFP: 

Very Thin Quad Flat Package

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 2009 - 2015 Microchip Technology Inc.

DS00002005A-page 6

USB2250/50i/51/51i

2.0

PIN CONFIGURATION

FIGURE 2-1:

128-PIN VTQFP DIAGRAM

97

MS_D6

99

MS_D3

100

MS_D7

101

MS_SCLK

102

VSS

103

TEST

104

VDD33

106

MA7

107

MA13

108

MA6

109

MA8

110

MA5

111

MA9

112

MA4

113

MA11

114

MA3

115

nMRD

116

MA2

117

CF_DMARQ / RXD

SCL / xD_ID

CF_DMACK

120

LED  

121

VBUS_DET

122

VSS

123

XTAL2

124

XTAL1 (CLKIN)

125

VDD18PLL

126

VSS

127

RBIAS

128

VDD33

64

nRESET

63

CF_D5

62

CF_D12

61

CF_D4

60

CF_D11

59

CF_D3

58

CF_nCD

57

SM_nCD

56

SM_nB/R

55

SM_nRE

54

SM_nCE

53

SM_CLE

52

SM_ALE

51

VSS

50

VDD33

49

VDD18

48

SM_nWE

47

SM_nWP

46

SM_D0

45

SM_D1

44

SM_D2

43

SM_D3

42

SM_D4

41

SM_D5

40

SM_D6

39

SM_D7

38

SM_nWPS

37

MD0

36

MD1

35

MD2

34

MD3

33

MD7

96

MS

_

D

2

95

MS

_

D

4

94

M

S

_D0 /

 MS

_

S

DIO

93

MS

_

D

5

92

MS

_

D

1

91

MS

_

B

S

90

CF

_D10

89

CF

_D9

88

CF

_D2

87

CF

_D8

86

CF

_D1

85

CF

_D0

84

CF

_SA0

83

CF

_SA1

82

CF

_SA2

81

VS

S

80

CF

_IORDY

79

CF

_nRESET

78

CR

D_PW

R1

77

V

DD33

76

CR

D_PW

R2

75

VS

S

74

CF

_IRQ

73

CF

_nIOW

72

CF

_nIOR

71

CF

_nCS0

70

CF

_D15

69

CF

_D7

68

CF

_D14

67

CF

_D6

66

CF

_D13

65

V

DD33

USB225X

128 VTQFP 

(Top View)

1

MA12

2

MA15

3

nM

WR

4

MA14

5

SD

A

6

REG_EN

7

USB+

8

US

B-

9

VSS

10

SD_

D

1

11

SD_

D

6

12

SD_

D

0

13

SD_

D

7

15

VDD33

16

17

VSS

18

SD_CLK

19

SD_

D

5

20

SD_

C

MD

21

SD_

D

4

22

SD_

D

3

23

SD_

D

2

24

MA10

25

MA1 /

 CL

K_S

E

L1

26

nMCE

27

MA0 /

 CL

K_S

E

L0

28

MA16

29

MD

6

30

MD

5

31

MD

4

SD

_n

CD

14

CRD

_PWR

0

118

CRD

_PWR

3

119

32

98

MS_INS

105

SD_WP

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 2009 - 2015 Microchip Technology Inc.

DS00002005A-page 7

USB2250/50i/51/51i

3.0

BLOCK DIAGRAM

FIGURE 3-1:

USB2250/50I/51/51I BLOCK DIAGRAM

FMDU

CTL

8051

PROCESSOR

SFR 

RAM

CF/

GPIO (16)

MS

SM

RAM

USB 

Host

AUTO_CBW 

PROC

PHY

FMI

XDATA  BRIDGE

+ BUS ARBITER

BUS 

INTFC

BUS 

INTFC

BUS 

INTFC

    

EP0 TX

EP0 RX

EP2 TX

EP2 RX

EP1 RX
EP1 TX

ROM

64 KB

RAM

10 KB

ADDR

MAP

PWR_FET1

PWR_FET3

CRD_PWR0

CRD_PWR1

CRD_PWR3

Clock 

Generation and 

Control

CRD_PWR2

SD/

MMC

4K

total

PWR_FET0

PWR_FET2

GPIOs

Program Memory I/O Bus

3.3 V

1.8 V Reg

VDD18

3.3 V

VDD18PLL

PLL

24 MHz 

Crystal

SIE

CTL

1.8 V Reg

USB2250 / USB2251

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 2009 - 2015 Microchip Technology Inc.

DS00002005A-page 8

USB2250/50i/51/51i

4.0

PIN TABLE

4.1

128-Pin Package

TABLE 4-1:

128-PIN VTQFP PACKAGE

COMPACT FLASH INTERFACE (28 PINS)

CF_D0

CF_D1

CF_D2

CF_D3

CF_D4

CF_D5

CF_D6

CF_D7

CF_D8

CF_D9

CF_D10

CF_D11

CF_D12

CF_D13

CF_D14

CF_D15

CF_nIOR

CF_nIOW

CF_IRQ

CF_nRESET

CF_IORDY

CF_nCS0

CF_DMACK

CF_SA0

CF_SA1

CF_SA2

CF_nCD

CF_DMARQ

SMARTMEDIA INTERFACE (17 PINS)

SM_D0

SM_D1

SM_D2

SM_D3

SM_D4

SM_D5

SM_D6

SM_D7

SM_ALE

SM_CLE

SM_nRE

SM_nWE

SM_nWP

SM_nB/R

SM_nCE

SM_nCD

SM_nWPS

MEMORY STICK INTERFACE (11 PINS)

MS_BS

MS_D0 / MS_SDIO

MS_SCLK

MS_INS

MS_D1

MS_D2

MS_D3

MS_D4

MS_D5

MS_D6

MS_D7

SECURE DIGITAL / MULTIMEDIACARD INTERFACE (12 PINS)

SD_CMD

SD_CLK

SD_D0

SD_D1

SD_D2

SD_D3

SD_WP

SD_nCD

SD_D4

SD_D5

SD_D6

SD_D7

USB INTERFACE (6 PINS)

USB+

USB-

RBIAS

XTAL2

XTAL1 (CLKIN)

REG_EN

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USB2250/50i/51/51i

DS00002005A-page 9

 2009 - 2015 Microchip Technology Inc.

MEMORY/IO INTERFACE (28 PINS)

MA0 / CLK_SEL0

MA1 / CLK_SEL1

MA2

MA3

MA4

MA5

MA6

MA7

MA8

MA9

MA10

MA11

MA12

MA13

MA14

MA15

MA16

MD0

MD1

MD2

MD3

MD4

MD5

MD6

MD7

nMRD

nMWR

nMCE

MISC (10 PINS)

nRESET

VBUS_DET

SCL / xD_ID

SDA

 LED

CRD_PWR0

CRD_PWR1

CRD_PWR2

CRD_PWR3

TEST

DIGITAL, POWER (16 PINS)

(6) VDD33

(8) VSS

VDD18

VDD18PLL

TOTAL 128

TABLE 4-1:

128-PIN VTQFP PACKAGE (CONTINUED) 

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 2009 - 2015 Microchip Technology Inc.

DS00002005A-page 10

USB2250/50i/51/51i

5.0

PIN DESCRIPTIONS

This section provides a detailed description of each signal. The signals are arranged in functional groups according to
their associated interface. The pin descriptions are applied when using the internal default firmware and can be refer-
enced in 

Section 7.0, "Configuration Options," on page 21

. Please reference 

Section 1.1, "Acronyms," on page 5

 for a

list of the acronyms used.

The “n” symbol in the signal name indicates that the active, or asserted, state occurs when the signal is at a low voltage
level. When “n” is not present in the signal name, the signal is asserted at the high voltage level.

The terms assertion and negation are used exclusively. This is done to avoid confusion when working with a mixture of
“active low” and “active high” signals. The term assert, or assertion, indicates that a signal is active, independent of
whether that level is represented by a high or low voltage. The term negate, or negation, indicates that a signal is inac-
tive.

5.1

128-Pin VTQFP Pin Descriptions

TABLE 5-1:

USB2250/50I/51/51I 128-PIN VTQFP PIN DESCRIPTIONS

Name

Symbol

128-Pin 

VTQFP

Buffer 

Type

Description

COMPACT FLASH (CF) INTERFACE

CF Chip Select 0

CF_nCS0

71

O12PU

This pin is the active low chip select 0 signal for 
the task file registers of the CF ATA device in 
True IDE mode. This pin has a weak internal 
pull-up resistor.

CF Register 
Address

CF_SA[2:0]

82
83
84

I/O12

These pins are the register select address bits 
for the CF ATA device.

CF Interrupt

CF_IRQ

74

IPD

This is the active high interrupt request signal 
from the CF device. This pin has a weak internal 
pull-down resistor.

CF Data 15-8

CF_D[15:8] /

70
68
66
62
60
90
89
87

I/O12PD

CF_D[15:8]: These pins are the bi-directional 
data signals CF_D15 - CF_D8 in True IDE mode 
data transfer.

In True IDE mode, all task file register 
operations occur on CF_D[7:0], while data 
transfer occurs on CF_D[15:0].

These bi-directional data signals have weak 
internal pull-down resistors.

CF Data 7-0

CF_D[7:0]

69
67
63
61
59
88
86
85

I/O12PD

CF_D[7:0]: These pins are the bi-directional 
data signals CF_D7 - CF_D0 in True IDE mode 
data transfer. In True IDE mode, all of the task 
file register operations occur on CF_D[7:0], 
while data transfer occurs on CF_D[15:0].

These bi-directional data signals have weak 
internal pull-down resistors.

IO Ready

CF_IORDY

80

IPU

This pin is the active high input signal for 
IORDY. This pin has a weak internal pull-up 
resistor.

CF Card 
Detection1

CF_nCD

58

I/O12

Designates as the Compact Flash card 
detection pin.

CF Hardware 
Reset

CF_RESET_N

79

O12

This pin is an active low hardware reset signal 
to the CF device.

CF IO Read

CF_nIOR

72

O12

This pin is an active low read strobe signal for 
the CF device.

CF IO Write 
Strobe

CF_nIOW

73

O12

This pin is an active low write strobe signal for 
the CF device.

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 2009 - 2015 Microchip Technology Inc.

DS00002005A-page 1

General Description

The Microchip USB2250/50i/51/51i is a USB 2.0 com-
pliant, Hi-Speed mass storage class peripheral control-
ler intended for reading and writing to more than 24
popular flash media formats from the CompactFlash

®

(CF), SmartMedia

TM

 (SM), xD-Picture Card

TM

 (xD)

1

,

Memory Stick

®

 (MS), Secure Digital (SD), and MultiMe-

diaCard

TM

 (MMC) families. 

The USB2250/50i/51/51i is a fully integrated, single
chip solution capable of ultra high performance opera-
tion. Average sustained transfer rates exceeding 35
MB/s are possible if the media and host can support
those rates. 

Highlights

• 128-pin VTQFP (14x14 mm) RoHS compliant 

package

• Targeted for applications in which single or 

"combo" media sockets are used

• Supports multiple simultaneous card insertions
• Flexible assignment of number of LUNs and how 

card types are associated with the LUNs

• Hardware-controlled data flow architecture for all 

self-mapped media

• Pipelined hardware support for access to non-

self-mapped media

• Order number with “i” denotes the version that 

supports the industrial temperature range of -40ºC 
to 85ºC

Hardware Features

• Single chip flash media controller with non-multi-

plexed interface for independent card sockets

• Flash Media Specification Revision Compliance

- CompactFlash 4.1
- Secure Digital 2.0
- MultiMediaCard 4.2

• MMC Streaming Mode support

- Memory Stick 1.43
- Memory Stick Pro Format 1.02
- Memory Stick Duo Format 1.10
- Memory Stick Pro-HG Duo Format 1.01
- xD-Picture Card 1.2
- SmartMedia 1.3

• Extended configuration options

- xD player mode operation 
- Socket switch polarities, etc.

• Media Activity LED
• On board 24 MHz crystal driver circuit
• Optional external 24 MHz clock input

- 4 Independent internal card power FETs
- 200 mA each 
- "Fold-back" short circuit protection

• 8051 8-bit microprocessor

- 60 MHz - single cycle execution
- 64 KB ROM | 14 KB RAM

• Internal regulator for 1.8 V core operation
• Optimized pinout improves signal routing which 

eases implementation for improved signal integ-
rity

OEM Selectable

• Vendor, product, and language IDs
• Manufacturer ID and product strings (28 charac-

ter)

• Serial number string (12h digit max)
• Customizable vendor specific data by optional 

use of external serial EEPROM

• Bus- or self-powered selection
• LED blink interval or duration
• Internal power FET configuration

Software Features

• Optimized for low latency interrupt handling
• Reduced memory footprint
• Device Firmware Upgrade (DFU) support of exter-

nal EEPROM or External Flash
- Assembly line support
- End user field upgrade support
- DFU Package consists of driver, firmware, 

sample DFU application and source code, 
DFU driver API

• Optional custom firmware with up to 128 KB 

external ROM 

Applications

• Flash Media Card Reader/Writer
• Printers
• Desktop and Mobile PCs
• Consumer A/V
• Media Players/Viewers
• Vista ReadyBoost

TM

1.) xD-Picture Card not applicable to USB2251.

USB2250/50i/51/51i

Ultra Fast USB 2.0 Multi-Slot Flash Media Controller

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USB2250/50i/51/51i

DS00002005A-page 2

 2009 - 2015 Microchip Technology Inc.

TO OUR VALUED CUSTOMERS

It is our intention to provide our valued customers with the best documentation possible to ensure successful use of your Microchip
products. To this end, we will continue to improve our publications to better suit your needs. Our publications will be refined and
enhanced as new volumes and updates are introduced. 

If you have any questions or comments regarding this publication, please contact the Marketing Communications Department via
E-mail at 

docerrors@microchip.com

. We welcome your feedback.

Most Current Data Sheet

To obtain the most up-to-date version of this data sheet, please register at our Worldwide Web site at:

http://www.microchip.com

You can determine the version of a data sheet by examining its literature number found on the bottom outside corner of any page. 
The last character of the literature number is the version number, (e.g., DS30000000A is version A of document DS30000000).

Errata

An errata sheet, describing minor operational differences from the data sheet and recommended workarounds, may exist for cur-
rent devices. As device/documentation issues become known to us, we will publish an errata sheet. The errata will specify the
revision of silicon and revision of document to which it applies.

To determine if an errata sheet exists for a particular device, please check with one of the following:
• Microchip’s Worldwide Web site; 

http://www.microchip.com

• Your local Microchip sales office (see last page)

When contacting a sales office, please specify which device, revision of silicon and data sheet (include -literature number) you are
using.

Customer Notification System

Register on our web site at 

www.microchip.com

 to receive the most current information on all of our products.

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 2009 - 2015 Microchip Technology Inc.

DS00002005A-page 3

USB2250/50i/51/51i

Table of Contents

1.0 Introduction  ..................................................................................................................................................................................... 4
2.0 Pin Configuration  ............................................................................................................................................................................ 6
3.0 Block Diagram ................................................................................................................................................................................. 7
4.0 Pin Table  ......................................................................................................................................................................................... 8
5.0 Pin Descriptions  ............................................................................................................................................................................ 10
6.0 Pin Reset State Table  ................................................................................................................................................................... 17
7.0 Configuration Options  ................................................................................................................................................................... 21
8.0 AC Specifications  .......................................................................................................................................................................... 32
9.0 DC Parameters  ............................................................................................................................................................................. 34
10.0 Package Outline .......................................................................................................................................................................... 38
Appendix A: Data Sheet Revision History ........................................................................................................................................... 39
Product Identification System  ............................................................................................................................................................. 40
The Microchip Web Site  ...................................................................................................................................................................... 41
Customer Change Notification Service  ............................................................................................................................................... 41
Customer Support  ............................................................................................................................................................................... 41

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DS00002005A-page 4

USB2250/50i/51/51i

1.0

INTRODUCTION

The Microchip USB2250/50i/51/51i is a flash media card reader solution fully compliant with the USB 2.0 specification.
All required resistors on the USB ports are integrated into the device. This includes all series termination resistors on
D+ and D– pins and all required pull-down and pull-up resistors. The over-current sense inputs for the downstream fac-
ing ports have internal pull-up resistors.

Hardware Features

• Single chip flash media controller

• USB2250/USB2251 supports the commercial temperature range of 0°C to +70°C

• USB2250i/USB2251i supports the industrial temperature range of -40°C to +85°C

• 8051 8-bit microprocessor

- 60 MHz - single cycle execution

- 64 KB ROM |14 KB RAM

• Integrated regulator for 1.8 V core operation

• Flash Media Card Specification Revision Compliance

• Compact Flash 4.1

- CF UDMA Modes 0-4

- CF PIO Modes 0-6

• Secure Digital 2.0 

- HS-SD and HC-SD

- TransFlash™ and reduced form factor media 

• MultiMediaCard 4.2

- 1/4/8 bit MMC

• Memory Stick 1.43 

• Memory Stick Pro Format 1.02

• Memory Stick Pro-HG Duo Format 1.01 

- Memory Stick, MS Duo, HS-MS, MS Pro-HG, MS Pro

• Memory Stick Duo 1.10

• Smart Media 1.3

• xD-Picture Card 1.2

Software Features

• If the OEM is using an external EEPROM, the following features are available:

- Customizable vendor, product, and device ID’s

- 12-hex digits maximum for the serial number string

- 28-character manufacturer ID and product strings for the flash media reader/writer

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USB2250/50i/51/51i

DS00002005A-page 5

 2009 - 2015 Microchip Technology Inc.

1.1

Acronyms

ATA:

 Advanced Technology Attachment

CFC: 

Compact Flash Controller

FET: 

Field Effect Transistor

LUN: 

Logical Unit Number

MMC: MultiMediaCard

MSC: 

Memory Stick Controller

PLL: Phase-Locked 

Loop

RoHS: 

Restriction of Hazardous Substances Directive

RXD: 

Received eXchange Data

SDC: Secure 

Digital 

Controller

SIE: 

Serial Interface Engine

SMC: 

SmartMedia Controller

True IDE Mode:  True Integrated Drive Electronics Mode

TXD: 

Transmit eXchange Data

UART: Universal 

Asynchronous 

Receiver-Transmitter

UCHAR: Unsigned 

Character

UINT: 

Unsigned Integer

VTQFP: 

Very Thin Quad Flat Package

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DS00002005A-page 6

USB2250/50i/51/51i

2.0

PIN CONFIGURATION

FIGURE 2-1:

128-PIN VTQFP DIAGRAM

97

MS_D6

99

MS_D3

100

MS_D7

101

MS_SCLK

102

VSS

103

TEST

104

VDD33

106

MA7

107

MA13

108

MA6

109

MA8

110

MA5

111

MA9

112

MA4

113

MA11

114

MA3

115

nMRD

116

MA2

117

CF_DMARQ / RXD

SCL / xD_ID

CF_DMACK

120

LED  

121

VBUS_DET

122

VSS

123

XTAL2

124

XTAL1 (CLKIN)

125

VDD18PLL

126

VSS

127

RBIAS

128

VDD33

64

nRESET

63

CF_D5

62

CF_D12

61

CF_D4

60

CF_D11

59

CF_D3

58

CF_nCD

57

SM_nCD

56

SM_nB/R

55

SM_nRE

54

SM_nCE

53

SM_CLE

52

SM_ALE

51

VSS

50

VDD33

49

VDD18

48

SM_nWE

47

SM_nWP

46

SM_D0

45

SM_D1

44

SM_D2

43

SM_D3

42

SM_D4

41

SM_D5

40

SM_D6

39

SM_D7

38

SM_nWPS

37

MD0

36

MD1

35

MD2

34

MD3

33

MD7

96

MS

_

D

2

95

MS

_

D

4

94

M

S

_D0 /

 MS

_

S

DIO

93

MS

_

D

5

92

MS

_

D

1

91

MS

_

B

S

90

CF

_D10

89

CF

_D9

88

CF

_D2

87

CF

_D8

86

CF

_D1

85

CF

_D0

84

CF

_SA0

83

CF

_SA1

82

CF

_SA2

81

VS

S

80

CF

_IORDY

79

CF

_nRESET

78

CR

D_PW

R1

77

V

DD33

76

CR

D_PW

R2

75

VS

S

74

CF

_IRQ

73

CF

_nIOW

72

CF

_nIOR

71

CF

_nCS0

70

CF

_D15

69

CF

_D7

68

CF

_D14

67

CF

_D6

66

CF

_D13

65

V

DD33

USB225X

128 VTQFP 

(Top View)

1

MA12

2

MA15

3

nM

WR

4

MA14

5

SD

A

6

REG_EN

7

USB+

8

US

B-

9

VSS

10

SD_

D

1

11

SD_

D

6

12

SD_

D

0

13

SD_

D

7

15

VDD33

16

17

VSS

18

SD_CLK

19

SD_

D

5

20

SD_

C

MD

21

SD_

D

4

22

SD_

D

3

23

SD_

D

2

24

MA10

25

MA1 /

 CL

K_S

E

L1

26

nMCE

27

MA0 /

 CL

K_S

E

L0

28

MA16

29

MD

6

30

MD

5

31

MD

4

SD

_n

CD

14

CRD

_PWR

0

118

CRD

_PWR

3

119

32

98

MS_INS

105

SD_WP

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USB2250/50i/51/51i

3.0

BLOCK DIAGRAM

FIGURE 3-1:

USB2250/50I/51/51I BLOCK DIAGRAM

FMDU

CTL

8051

PROCESSOR

SFR 

RAM

CF/

GPIO (16)

MS

SM

RAM

USB 

Host

AUTO_CBW 

PROC

PHY

FMI

XDATA  BRIDGE

+ BUS ARBITER

BUS 

INTFC

BUS 

INTFC

BUS 

INTFC

    

EP0 TX

EP0 RX

EP2 TX

EP2 RX

EP1 RX
EP1 TX

ROM

64 KB

RAM

10 KB

ADDR

MAP

PWR_FET1

PWR_FET3

CRD_PWR0

CRD_PWR1

CRD_PWR3

Clock 

Generation and 

Control

CRD_PWR2

SD/

MMC

4K

total

PWR_FET0

PWR_FET2

GPIOs

Program Memory I/O Bus

3.3 V

1.8 V Reg

VDD18

3.3 V

VDD18PLL

PLL

24 MHz 

Crystal

SIE

CTL

1.8 V Reg

USB2250 / USB2251

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USB2250/50i/51/51i

4.0

PIN TABLE

4.1

128-Pin Package

TABLE 4-1:

128-PIN VTQFP PACKAGE

COMPACT FLASH INTERFACE (28 PINS)

CF_D0

CF_D1

CF_D2

CF_D3

CF_D4

CF_D5

CF_D6

CF_D7

CF_D8

CF_D9

CF_D10

CF_D11

CF_D12

CF_D13

CF_D14

CF_D15

CF_nIOR

CF_nIOW

CF_IRQ

CF_nRESET

CF_IORDY

CF_nCS0

CF_DMACK

CF_SA0

CF_SA1

CF_SA2

CF_nCD

CF_DMARQ

SMARTMEDIA INTERFACE (17 PINS)

SM_D0

SM_D1

SM_D2

SM_D3

SM_D4

SM_D5

SM_D6

SM_D7

SM_ALE

SM_CLE

SM_nRE

SM_nWE

SM_nWP

SM_nB/R

SM_nCE

SM_nCD

SM_nWPS

MEMORY STICK INTERFACE (11 PINS)

MS_BS

MS_D0 / MS_SDIO

MS_SCLK

MS_INS

MS_D1

MS_D2

MS_D3

MS_D4

MS_D5

MS_D6

MS_D7

SECURE DIGITAL / MULTIMEDIACARD INTERFACE (12 PINS)

SD_CMD

SD_CLK

SD_D0

SD_D1

SD_D2

SD_D3

SD_WP

SD_nCD

SD_D4

SD_D5

SD_D6

SD_D7

USB INTERFACE (6 PINS)

USB+

USB-

RBIAS

XTAL2

XTAL1 (CLKIN)

REG_EN

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USB2250/50i/51/51i

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 2009 - 2015 Microchip Technology Inc.

MEMORY/IO INTERFACE (28 PINS)

MA0 / CLK_SEL0

MA1 / CLK_SEL1

MA2

MA3

MA4

MA5

MA6

MA7

MA8

MA9

MA10

MA11

MA12

MA13

MA14

MA15

MA16

MD0

MD1

MD2

MD3

MD4

MD5

MD6

MD7

nMRD

nMWR

nMCE

MISC (10 PINS)

nRESET

VBUS_DET

SCL / xD_ID

SDA

 LED

CRD_PWR0

CRD_PWR1

CRD_PWR2

CRD_PWR3

TEST

DIGITAL, POWER (16 PINS)

(6) VDD33

(8) VSS

VDD18

VDD18PLL

TOTAL 128

TABLE 4-1:

128-PIN VTQFP PACKAGE (CONTINUED) 

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USB2250/50i/51/51i

5.0

PIN DESCRIPTIONS

This section provides a detailed description of each signal. The signals are arranged in functional groups according to
their associated interface. The pin descriptions are applied when using the internal default firmware and can be refer-
enced in 

Section 7.0, "Configuration Options," on page 21

. Please reference 

Section 1.1, "Acronyms," on page 5

 for a

list of the acronyms used.

The “n” symbol in the signal name indicates that the active, or asserted, state occurs when the signal is at a low voltage
level. When “n” is not present in the signal name, the signal is asserted at the high voltage level.

The terms assertion and negation are used exclusively. This is done to avoid confusion when working with a mixture of
“active low” and “active high” signals. The term assert, or assertion, indicates that a signal is active, independent of
whether that level is represented by a high or low voltage. The term negate, or negation, indicates that a signal is inac-
tive.

5.1

128-Pin VTQFP Pin Descriptions

TABLE 5-1:

USB2250/50I/51/51I 128-PIN VTQFP PIN DESCRIPTIONS

Name

Symbol

128-Pin 

VTQFP

Buffer 

Type

Description

COMPACT FLASH (CF) INTERFACE

CF Chip Select 0

CF_nCS0

71

O12PU

This pin is the active low chip select 0 signal for 
the task file registers of the CF ATA device in 
True IDE mode. This pin has a weak internal 
pull-up resistor.

CF Register 
Address

CF_SA[2:0]

82
83
84

I/O12

These pins are the register select address bits 
for the CF ATA device.

CF Interrupt

CF_IRQ

74

IPD

This is the active high interrupt request signal 
from the CF device. This pin has a weak internal 
pull-down resistor.

CF Data 15-8

CF_D[15:8] /

70
68
66
62
60
90
89
87

I/O12PD

CF_D[15:8]: These pins are the bi-directional 
data signals CF_D15 - CF_D8 in True IDE mode 
data transfer.

In True IDE mode, all task file register 
operations occur on CF_D[7:0], while data 
transfer occurs on CF_D[15:0].

These bi-directional data signals have weak 
internal pull-down resistors.

CF Data 7-0

CF_D[7:0]

69
67
63
61
59
88
86
85

I/O12PD

CF_D[7:0]: These pins are the bi-directional 
data signals CF_D7 - CF_D0 in True IDE mode 
data transfer. In True IDE mode, all of the task 
file register operations occur on CF_D[7:0], 
while data transfer occurs on CF_D[15:0].

These bi-directional data signals have weak 
internal pull-down resistors.

IO Ready

CF_IORDY

80

IPU

This pin is the active high input signal for 
IORDY. This pin has a weak internal pull-up 
resistor.

CF Card 
Detection1

CF_nCD

58

I/O12

Designates as the Compact Flash card 
detection pin.

CF Hardware 
Reset

CF_RESET_N

79

O12

This pin is an active low hardware reset signal 
to the CF device.

CF IO Read

CF_nIOR

72

O12

This pin is an active low read strobe signal for 
the CF device.

CF IO Write 
Strobe

CF_nIOW

73

O12

This pin is an active low write strobe signal for 
the CF device.

Maker
Microchip Technology Inc.
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